Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Kopera, D; Horejsi, R; Werner, S; Moeller, R.
Injection lipolysis for reduction of saddlebag trochanteric bulges--half-side controlled pilot study.
J Dtsch Dermatol Ges. 2008; 6(4):287-290
Doi: 10.1111/j.1610-0387.2007.06571.x
Web of Science
PubMed
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FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Kopera Daisy
- Co-Autor*innen der Med Uni Graz
- Horejsi Renate
- Möller Reinhard
- Werner Stefan
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- Abstract:
- Phosphatidylcholine, a lecithin extracted from soybeans can reduce serum cholesterol to some extent. Intravenous use may prevent fat embolism in polytrauma patients. When injected intralesionally in a formulation containing also deoxycholate and ethanol it is supposed to act as "fat burner" to reduce undesired fat deposits; there is little evidence-based scientific support for this indication. To evaluate the capability of phosphatidylcholine + deoxycholate + ethanol (PPC/DC/E) to reduce body fat with a half-side pilot study for the reduction of saddlebag trochanteric bulges. PPC/DC/E was injected into the right posterior trochanteric areas three times at weeks 0, 3 and 6. Treatment areas and the same regions of the contralateral side as a control were evaluated by sonography. Tape measurements were taken and the thickness of the subcutaneous adipose tissue (SAT) was measured with an optical device (Lipometer) at baseline and at week 8 and week 20 (2 and 14 weeks after completing therapy). In this half-side trial, no significant reduction of subcutaneous fat was achieved after three treatments with PPC/DC/E when compared to the untreated side.Transient inflammatory reactions occurred in all patients. Only the commercially available formulation containing the three components was tested. The off-label use of PPC/DC/E as a "fat burner" did not produce measurable reduction of undesired trochanteric fat deposits.
- Find related publications in this database (using NLM MeSH Indexing)
- Adipose Tissue - drug effects
- Adipose Tissue - pathology
- Adult -
- Body Mass Index -
- Cosmetic Techniques -
- Drug Combinations -
- Female -
- Humans -
- Injections, Subcutaneous -
- Lipolysis - drug effects
- Middle Aged -
- Phosphatidylcholines - administration & dosage
- Pilot Projects -
- Skinfold Thickness -
- Thigh - pathology
- Tomography, Optical -
- Find related publications in this database (Keywords)
- phosphatidylcholine
- deoxycholate
- injection lipolysis
- Lipometer (R)