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Mozaffarieh, M; Sacu, S; Benesch, T; Wedrich, A.
Subretinal hemorrhages secondary to age-related macular degeneration: psychological and vision-related functional perspectives.
Ophthalmologica. 2008; 222(3):199-204 Doi: 10.1159/000126084
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Führende Autor*innen der Med Uni Graz
Wedrich Andreas
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Abstract:
PURPOSE: To assess psychological, visual and functional aspects associated with subretinal hemorrhages secondary to age-related macular degeneration (AMD). METHOD: In this prospective, comparative, longitudinal study, 90 eyes of 90 patients with a subretinal hemorrhage, secondary to AMD, of at least 1 disk diameter were treated with recombinant tissue plasminogen activator (rTPA) and gas, and compared to 25 eyes of 25 controls. Outcome measures were: (1) visual acuity, (2) self-reported vision-related quality of life (Visual Function 14-item questionnaire) and (3)Hospital Anxiety and Depression (HAD) scores. Visual acuity and questionnaire responses were recorded prior to as well as 2 weeks and 4 months after treatment. RESULTS: Improvements across objective visual acuity and vision-related functional measures, assessed at 2 weeks and 4 months, were significantly higher in patients who had rTPA and gas injections than in controls (p < 0.01). Patients were significantly more distressed at their 2-week follow-up in comparison to controls (HAD scores p < 0.01). Comparisons to controls showed no significant difference in psychological scores at the 4-month follow-up (p > 0.32). CONCLUSIONS: Patients with subretinal hemorrhages secondary to AMD are psychologically distressed as a result of acute loss of vision. More attention should be given to strategies that teach patients to cope with acute vision loss and thereby psychological disorder.
Find related publications in this database (using NLM MeSH Indexing)
Aged -
Female -
Fibrinolytic Agents - administration and dosage
Fluorocarbons - administration and dosage
Follow-Up Studies -
Humans -
Injections -
Macular Degeneration - complications
Male -
Prognosis -
Prospective Studies -
Quality of Life -
Questionnaires -
Recombinant Proteins -
Retinal Hemorrhage - etiology
Tissue Plasminogen Activator - administration and dosage
Visual Acuity - physiology
Vitreous Body -

Find related publications in this database (Keywords)
psychological distress
vision-related functioning
subretinal hemorrhage
age-related macular degeneration
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