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Selected Publication:
ESTERBAUER, H; DIEBERROTHENEDER, M; STRIEGL, G; WAEG, G.
ROLE OF VITAMIN-E IN PREVENTING THE OXIDATION OF LOW-DENSITY-LIPOPROTEIN
AMER J CLIN NUTR. 1991; 53(1): S314-S321.
Doi: 10.1093/ajcn/53.1.314S
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- Co-authors Med Uni Graz
- Dieber-Rotheneder Martina
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- Abstract:
- The fatty acid composition, antioxidants, and the oxidation resistance of the low-density lipoproteins (LDL) from a number of different donors were determined. The oxidation resistance of LDL, as determined in vitro by the duration of the lag-phase in copper ion-induced oxidation, did not correlate with the alpha-tocopherol content of the LDL. By supplementating plasma with vitamin E, the alpha-tocopherol content of LDL could be increased from approximately 9 to 30 mol/mol LDL and also the oxidative resistance increased nearly linearly with increasing alpha-tocopherol content. The results indicate that alpha-tocopherol is an important, yet not the only parameter that determines the oxidation resistance of LDL.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Antioxidants - metabolism
- Fatty Acids - analysis
- Fatty Acids, Unsaturated - analysis
- Female - analysis
- Humans - analysis
- Lipid Peroxidation - analysis
- Lipoproteins, LDL - analysis
- Male - analysis
- Oxidation-Reduction - analysis
- Vitamin E - pharmacology
- Find related publications in this database (Keywords)
- VITAMIN-E
- ATHEROSCLEROSIS
- LOW DENSITY LIPOPROTEIN
- LIPID PEROXIDATION