Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Schernthaner, G; Kostner, GM; Dieplinger, H; Prager, R; Mühlhauser, I.
Apolipoproteins (A-I, A-II, B), Lp(a) lipoprotein and lecithin: cholesterol acyltransferase activity in diabetes mellitus.
ATHEROSCLEROSIS. 1983; 49(3): 277-293.
Doi: 10.1016/0021-9150(83)90139-9
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- Co-Autor*innen der Med Uni Graz
- Kostner Gerhard
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- Abstract:
- Concentrations of HDL cholesterol, apolipoprotein (apo) A-I and apo A-II were found to be significantly decreased in patients with insulin-dependent diabetes (IDD) and non-insulin-dependent diabetes (NIDD) compared with carefully selected controls matched for sex, age and body weight. LDL cholesterol and apo B levels did not differ significantly between diabetics and controls. Concentrations of lipoprotein Lp(a), an independent risk factor for coronary artery disease in non-diabetics, were above 20 mg/dl in only 14% of diabetics and in 5% of controls. LCAT activity was normal in diabetics, irrespective of type of diabetes, sex and age of patients. No correlation between HbA1 and either HDL cholesterol or A-I and A-II was found in IDD and NIDD. A positive correlation between HbA1 and either triglyceride or VLDL triglyceride was noted in IDD and NIDD. There was also a positive correlation between insulin dosage in IDD and HDL cholesterol, apolipoprotein A-I and A-II.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Adult -
- Aged -
- Apolipoprotein A-I -
- Apolipoprotein A-II -
- Apolipoproteins - blood
- Apolipoproteins B - blood
- Cholesterol - blood
- Cholesterol, HDL - blood
- Cholesterol, LDL - blood
- Cholesterol, VLDL - blood
- Diabetes Mellitus - blood
- Diabetes Mellitus, Type 1 - blood
- Diabetes Mellitus, Type 2 - blood
- Female - blood
- Humans - blood
- Lipoprotein(a) - blood
- Lipoproteins - blood
- Lipoproteins, HDL - blood
- Lipoproteins, LDL - blood
- Lipoproteins, VLDL - blood
- Male - blood
- Middle Aged - blood
- Phosphatidylcholine-Sterol O-Acyltransferase - blood
- Triglycerides - blood