Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Bucsics, A; Holzer, P; Lembeck, F.
The substance P content of peripheral tissues in several mammals.
PEPTIDES. 1983; 4: 451-455.
Doi: 10.1016/0196-9781(83)90048-7
(- Case Report)
Web of Science
PubMed
FullText
FullText_MUG
Google Scholar
- Führende Autor*innen der Med Uni Graz
- Lembeck Fred
- Co-Autor*innen der Med Uni Graz
- Holzer Peter
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- Levels of substance P immunoreactivity (SPI) were determined in several skin and mucosal areas, in parts of the sympathetic nervous system, the urinary, biliary and respiratory systems of cats, rabbits and guinea-pigs, and in various skin and mucosal areas of humans by radioimmunoassay. Salient findings are (1) The general distribution pattern of SPI in rabbits was similar to that in rodents. (2) The highest SPI tissue levels were found in the sympathetic nervous system, notably in guinea-pigs. (3) The guinea-pig also had the highest SPI levels in ureter, urinary bladder and bile duct. (4) The aorta, pulmonary artery and portal vein of the rabbit contained very low amounts of SPI, the concentration in the carotid sinus being several fold higher. (5) Skin SPI content was generally highest in the cat, especially in the hindpaw-pad, and lowest in abdominal and back skin. (6) SPI levels found in postmortem human skin and mucosal samples are comparable to those found in other mammals. The observations are discussed in view of the sensory innervation of the various tissues.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Animals -
- Cats -
- Cornea - analysis
- Female - analysis
- Guinea Pigs - analysis
- Humans - analysis
- Male - analysis
- Middle Aged - analysis
- Mouth Mucosa - analysis
- Muscle, Smooth, Vascular - analysis
- Nasal Mucosa - analysis
- Rabbits - analysis
- Research Support, Non-U.S. Gov't - analysis
- Skin - analysis
- Species Specificity - analysis
- Substance P - analysis
- Sympathetic Nervous System - analysis
- Tissue Distribution - analysis
- Tongue - analysis