Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Brazier, J; Chmelar, D; Dubreuil, L; Feierl, G; Hedberg, M; Kalenic, S; Könönen, E; Lundgren, B; Malamou-Ladas, H; Nagy, E; Sullivan, A; Nord, CE; The ESCMID Study Group on Antimicrobial Resistance in Anaerobic Bacteria (ESGARAB).
European surveillance study on antimicrobial susceptibility of Gram-positive anaerobic cocci.
Int J Antimicrob Agents. 2008; 31(4):316-320
Doi: 10.1016/j.ijantimicag.2007.11.006
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Feierl Gebhard
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- Abstract:
- Gram-positive anaerobic cocci (GPAC) are a heterogeneous group of microorganisms frequently isolated from local and systemic infections. In this study, the antimicrobial susceptibilities of clinical strains isolated in 10 European countries were investigated. After identification of 299 GPAC to species level, the minimum inhibitory concentrations of penicillin, imipenem, clindamycin, metronidazole, vancomycin and linezolid were determined by the agar dilution method according to the Clinical and Laboratory Standards Institute. The majority of isolates were identified as Finegoldia magna and Parvimonas micra (formerly Peptostreptococcus micros), isolated from skin and soft tissue infections. All isolates were susceptible to imipenem, metronidazole, vancomycin and linezolid. Twenty-one isolates (7%) were resistant to penicillin (n=13) and/or to clindamycin (n=12). Four isolates were resistant to both agents. The majority of resistant isolates were identified as F. magna and originated from blood, abscesses and soft tissue infections.
- Find related publications in this database (using NLM MeSH Indexing)
- Anti-Bacterial Agents - pharmacology
- Drug Resistance, Bacterial -
- Europe - epidemiology
- Gram-Negative Anaerobic Cocci - drug effects
- Gram-Positive Bacterial Infections - epidemiology
- Humans -
- Microbial Sensitivity Tests -
- Population Surveillance -
- beta-Lactamases - biosynthesis
- Find related publications in this database (Keywords)
- antimicrobial resistance
- clinical isolates
- anaerobic cocci