Medizinische Universität Graz - Research portal
Selected Publication:
Toplak, H; Schumacher, M; Eber, B; Luha, O; Klein, W; Krejs, GJ.
Microalbuminuria is no risk factor for restenosis following percutaneous transluminal coronary angioplasty.
Clin Investig. 1992; 70(11):1010-1012
Doi: 10.1007/BF00180310
Web of Science
PubMed
FullText
FullText_MUG
- Leading authors Med Uni Graz
- Toplak Hermann
- Co-authors Med Uni Graz
- Klein Werner
- Krejs Günter Josef
- Schumacher Martin
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- Abstract:
- Microalbuminuria is known to be associated with an increased risk for cardiovascular disease. It is detectable in acute myocardial infarction and could therefore also be a risk factor for reocclusion after percutaneous transluminal coronary angioplasty (PTCA). In our study follow-up coronary angiography was performed in 50 consecutive patients with a mean age of 56 years (38-70) on average 14 months after successful PTCA. Restenosis was defined as a decrease in diameter of 25% or more of the original result and one of at least 50% in vessel diameter. In the restenosis group there were 23 patients, and 27 showed no restenosis. The family history and anamnestic risk profile, results of the initially performed coronary angiography, and laboratory risk factors were comparable in the two groups. Median microalbumin was 11.2 mg/g creatinine in those with restenosis and 9.8 mg/g creatinine in those without. Using a cut-off of 10.0 mg/g creatinine, 12 of 23 patients with restenosis (52%) and 10 of 27 patients without (37%) were positive for microalbuminuria (NS). The incidence of microalbuminuria was higher in both groups compared to historical controls. Thus, in the restenosis group the incidence of microalbuminuria tended to be higher than in the nonrestenosis group, but since this difference did not reach statistical significance, it cannot be used to predict the risk of reocclusion after PTCA.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Albuminuria - complications
- Angioplasty, Balloon, Coronary -
- Biological Markers - urine
- Coronary Disease - therapy Coronary Disease - urine
- Humans -
- Incidence -
- Male -
- Middle Aged -
- Myocardial Infarction - epidemiology
- Recurrence -
- Risk Factors -
- Find related publications in this database (Keywords)
- CORONARY HEART DISEASE
- PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY
- RESTENSOSIS
- CARDIOVASCULAR RISK FACTORS
- MICROALBUMINURIA