Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Pristauz, G; Bauer, M; Maurer-Fellbaum, U; Rotky-Fast, C; Bader, AA; Haas, J; Lang, U.
Neonatal outcome and two-year follow-up after expectant management of second trimester rupture of membranes.
Int J Gynaecol Obstet. 2008; 101(3): 264-268.
Doi: 10.1016/j.ijgo.2007.12.007
Web of Science
PubMed
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FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Pristauz-Telsnigg Gunda
- Co-Autor*innen der Med Uni Graz
- Bader Arnim
- Haas Josef
- Lang Uwe
- Maurer-Fellbaum Ute
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- Abstract:
- OBJECTIVE: To assess neonatal outcome and 2-year follow-up of pregnancies complicated by second trimester preterm premature rupture of membranes (PPROM). METHODS: A retrospective review of obstetric and neonatal records for 87 pregnancies (56 singletons, 6 twins, 1 triplet) with PPROM between 14+0 and 24+6 weeks of gestation. Patients received antibiotics and steroids for fetal lung maturity once they reached 24 weeks of gestation. Placentas were examined histopathologically. Surviving infants were followed-up at 2 years of age. RESULTS: Median latency from PPROM to delivery was 4 days. Survival rate of 56 singletons was 45% (25/56); and 13 died in hospital. Survival rate of infants discharged from hospital was 23% (12/56). Chorioamnionitis was seen histologically in 42% (5/12) of surviving infants compared with 92% (12/13) of those that died in hospital. Of the 12 surviving infants, 50% had a normal neurological and developmental outcome at 2 years of age. CONCLUSION: Gestational age, birth weight, and histologic chorioamnionitis have prognostic importance in pregnancies complicated by PPROM. Surviving infants have a 50% chance of achieving an adequate health status at 2 years of age.
- Find related publications in this database (using NLM MeSH Indexing)
- Adrenal Cortex Hormones -
- Adult -
- Anti-Bacterial Agents - therapeutic use
- Chorioamnionitis - drug therapy
- Female -
- Fetal Death - etiology
- Fetal Membranes, Premature Rupture - diagnosis
- Fetal Organ Maturity - drug effects
- Follow-Up Studies -
- Gestational Age -
- Humans -
- Infant, Newborn -
- Infant, Premature, Diseases - mortality
- Medical Records -
- Obstetric Labor, Premature - therapy
- Pregnancy -
- Pregnancy Outcome -
- Pregnancy Trimester, Second -
- Retrospective Studies -
- Survival Rate -
- Time Factors -
- Find related publications in this database (Keywords)
- chorioamnionitis
- fetal risk
- neonatal outcome
- preterm premature rupture of membranes
- two-year follow-up