Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Mezger, M; Steffens, M; Beyer, M; Manger, C; Eberle, J; Toliat, MR; Wienker, TF; Ljungman, P; Hebart, H; Dornbusch, HJ; Einsele, H; Loeffler, J.
Polymorphisms in the chemokine (C-X-C motif) ligand 10 are associated with invasive aspergillosis after allogeneic stem-cell transplantation and influence CXCL10 expression in monocyte-derived dendritic cells.
Blood. 2008; 111(2):534-536
Doi: 10.1182/blood-2007-05-090928
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- Co-Autor*innen der Med Uni Graz
- Dornbusch Hans Jürgen
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- Abstract:
- Patients after allogeneic stem-cell transplantation (alloSCT) have an increased risk for invasive aspergillosis (IA). Here, recipients of an allograft with IA (n=81) or without IA (n=58) were screened for 84 single nucleotide polymorphisms in 18 immune relevant genes. We found 3 markers in chemokine (C-X-C motif) ligand 10 (CXCL10, 4q21, 11,101 C>T, P=.007; 1642 C
- Find related publications in this database (using NLM MeSH Indexing)
- Aspergillosis - blood
- Aspergillus fumigatus - immunology
- Cells, Cultured -
- Chemokine CXCL10 - blood
- Dendritic Cells - immunology
- Female -
- Genetic Predisposition to Disease -
- Hematologic Neoplasms - blood
- Humans -
- Male -
- Monocytes - immunology
- Polymorphism, Single Nucleotide - immunology
- Risk Factors -
- Stem Cell Transplantation -
- Transplantation, Homologous -