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Bilali, S; Pfeifer, J.
Anorectal manometry: are fatigue rate and fatigue rate index of any clinical importance?
Tech Coloproctol. 2005; 9(3): 225-228. Doi: 10.1007/s10151-005-0232-3
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Leading authors Med Uni Graz
Pfeifer Johann
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Abstract:
BACKGROUND: Loss of voluntary contraction of the external anal sphincter is thought to be a factor in fecal incontinence. During anal manometry, computerized systems produce several parameters including fatigue rate (FR), which is the basis for calculating the fatigue rate index (FRI). Our aim was to evaluate FR and FRI and their clinical importance in patients suffering from fecal incontinence or severe constipation. MATERIALS AND METHODS: All patients scheduled for an anal physiology work-up were included in the study. FR was determined by a computer program and FRI was calculated manually with the following equation: FRI (minutes) = [squeeze pressure (mm Hg) - resting pressure (mmHg)] / - FR (mmHg/min). FR and FRI were compared in patients suffering from fecal incontinence (group I) and severe constipation (group II). Furthermore, subgroups (<50 and > or = 50 years of age) were compared. Lastly, a possible relation between length of the high-pressure zone (HPZ) and FR and FRI was assessed. RESULTS: Between January 2000 and December 2004, 131 patients (96 with fecal incontinence, 35 with constipation) were studied. Both FR and FRI were similar between groups I and II; no significant differences were found when younger and older patients were compared within the same group. We also did not find any relation between HPZ length and either FR or FRI. CONCLUSIONS: FR and FRI do not seem to be helpful in routine colorectal practice for evaluating the strength of the external anal sphincter.
Find related publications in this database (using NLM MeSH Indexing)
Adult -
Age Distribution -
Aged -
Anal Canal - physiopathology
Cohort Studies - physiopathology
Constipation - diagnosis
Defecography - methods
Fecal Incontinence - diagnosis
Female - diagnosis
Humans - diagnosis
Incidence - diagnosis
Male - diagnosis
Manometry - diagnosis
Middle Aged - diagnosis
Muscle Contraction - physiology
Muscle Fatigue - physiology
Probability - physiology
Prognosis - physiology
Sensitivity and Specificity - physiology
Severity of Illness Index - physiology
Sex Distribution - physiology
Statistics, Nonparametric - physiology

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