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Selected Publication:
Schmut, O; Hofmann, H.
Preparation of gels from hyaluronate solutions.
Graefes Arch Clin Exp Ophthalmol. 1982; 218(6):311-314
Doi: 10.1007/BF02150446
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- Schmut Otto
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- Abstract:
- Stable, transparent gels can be prepared from hyaluronate solutions by adding CuSO4. The best gelation was found using solutions of 2 mg/ml hyaluronate in glass-distilled water at a pH of 6.2 after the addition of 1 mg/ml CuSO4. Methylation of the carboxyl groups of the hyaluronate completely abolished the gelation, indicating the importance of the carboxyl groups for the gel formation with Cu2+ ions. Gelation also depends on the molecular size of the hyaluronate, since hyaluronate was not able to form a gel after depolymerization with hyaluronidase.
- Find related publications in this database (using NLM MeSH Indexing)
- Animals -
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- Drug Compounding -
- Gels -
- Hyaluronic Acid - analogs and derivatives
- Hydrogen-Ion Concentration - analogs and derivatives
- Ophthalmic Solutions - analogs and derivatives
- Vitreous Body - metabolism