Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Becker, H; Zaunschirm, A; Muntean, W; Domej, W.
Fetal alcohol syndrome and malignant tumors
WIEN KLIN WOCHENSCHR. 1982; 94: 364-365.
(- Case Report)
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- Co-Autor*innen der Med Uni Graz
- Domej Wolfgang
- Muntean Eugen
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- Abstract:
- This paper presents the case report of a 2 year-old boy in whom a grade II fetal alcohol syndrome was diagnosed at 17 months. At 21 months, an embryonal rhabdomyosarcoma of the urinary bladder trigone was found, and the tumour excised. Polychemotherapy was initiated, but bone-marrow depression and death in septicaemic shock followed. The main autopsy findings included the demonstration of tumour remnants in the urinary bladder and prostate, and a severe acute purulent pyelonephritis. This is the fifth case of fetal alcohol syndrome in conjunction with a malignant tumour to be reported in the international literature. These cases do not show any uniformity as to tumour type. No conclusion can as yet be drawn as to whether there is a pathogenetic connection between the fetal alcohol syndrome and the occurrence of malignant tumours (as is the case with the fetal hydantoin syndrome and neuroblastoma), or whether these findings are purely coincidental. Clinicians and pathologists should, however, be advised to look more closely for even minimally pronounced forms of the fetal alcohol syndrome in children with embryonic tumours.
- Find related publications in this database (using NLM MeSH Indexing)
- Bladder - pathology
- Bladder Neoplasms - complications
- English Abstract - complications
- Female - complications
- Fetal Alcohol Syndrome - complications
- Humans - complications
- Infant - complications
- Male - complications
- Pregnancy - complications
- Rhabdomyosarcoma - complications