Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Kröll, W; Colombo, T; Wolf, G; Ramschak, H; Ferdinand, P; List, WF.
Does 6-Percent Hydroxyethylstarch (HES 200/0.60-0.66) Influence Hemostasis
CLIN HEMORHEOL. 1992; 12: 79-91.
Web of Science
- Führende Autor*innen der Med Uni Graz
- Kröll Wolfgang
- Co-Autor*innen der Med Uni Graz
- Wolf Gerhard
- Altmetrics:
- Abstract:
- Synthetic colloids especially dextrans given in amounts greater than 1.5 g/kg BW/day tend to interact with coagulation. 6% hydroxyethylstarch 200/0.6-0.66 is a new artificial colloid which offers a lot of advantages in contrast to dextrans and/or gelatine; these advantages are due to a large volume expanding effect. However it has not been clarified whether this new colloid has any influence on hemostasis. The present study deals with the effect of 6% HES 200/0.6-0.55 on coagulation parameters. 12 patients undergoing minor surgical interventions were given 500 ml of HES immediately before starting anaesthesia and on the 1.-3. postoperative day. All evaluated coagulation parameters (partial thrombin time, thrombin time, fibrinogen, antithrombine III, factor VIII-activity, thrombocytes and platelet aggregation) were within the normal range throughout the evaluated period. We conclude theat 6% HES 200/0.6-0.66 has no influence on coagulation except the dilutional one and can be recommended for patients in surgical settings as an excellent and safe artificial colloid.
- Find related publications in this database (Keywords)
- Hydroxyethylstarch
- Hemostasis
- Surgical Intervention
- Trauma