Selected Publication:
Gebauer, H; Pabst, MA.
Autoradiographic localization of 3H-GABA uptake in the thyroid gland of the rat.
Cell Tissue Res. 1981; 220(4):873-879
Web of Science
PubMed
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- Co-authors Med Uni Graz
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Pabst Maria-Anna
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- Abstract:
- The uptake of gamma-aminobutyric acid (GABA) in the thyroid gland of the rat was studied autoradiographically following in vitro incubation. High-affinity GABA uptake was localized in follicle cells, whereas C cells (parafollicular cells) in general did not accumulate GABA by high-affinity transport. The follicle cells were also the main sites of low-affinity GABA uptake. Additionally, some nerve fibres were found to accumulate GABA. The predominant localization of GABA uptake in follicle cells is discussed in view of a presumed role of GABA in thyroid function.
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Animals -
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Autoradiography -
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Biological Transport -
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Male -
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Rats -
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Rats, Inbred Strains -
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Thyroid Gland - cytology
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gamma-Aminobutyric Acid - metabolism