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Selected Publication:

Sinzinger, H; Fitscha, P; Peskar, BA.
Defects in the prostaglandin system. V. Inherited (?) disorder of prostacyclin degradation in the plasma (Wien-Döbling defect)
Wien Klin Wochenschr. 1985; 97(18):726-729 (- Case Report)
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Co-authors Med Uni Graz
Peskar Bernhard
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Abstract:
The case report is presented of a woman of child-bearing age who developed myocardial infarction. An extremely shortened in vitro half-life of PGI2 in plasma was detected in this patient. This new familial defect "Wien-Döbling", in the prostaglandin system might affect an essential coregulator of haemostatic balance in man. It is not known whether this short half-life of PGI2 in vitro is due to accelerated degradation or a failure in stabilization of this biologically active compound.
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