Lanzer, G; Pogglitsch, H; Tilz, GP.
Mechanisms of action and clinical importance of C3-nephritic-factor (author's transl)
ACTA MED AUST. 1981; 8(1): 7-13.
Web of SciencePubMed
The C3-nephritic-factor is an autoantibody specific against C3-convertases. This IgG-immunoglobulin is particularly found in patients suffering from membranoproliferative glomerulonephritis and causes a complement-activation under elimination of physiological regulator mechanisms. The clinical importance of this factor is discussed.
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