Medizinische Universität Graz - Research portal
Selected Publication:
Leithner, C; Sinzinger, H; Peskar, BA.
Increased plasma levels of 6-oxo-prostaglandin F1 alpha, a stable metabolite of prostacyclin, in acute kidney transplant rejection.
Prostaglandins Med. 1981; 7(1):15-18
Doi: 10.1016/0161-4630(81)90003-3
Web of Science
PubMed
FullText
FullText_MUG
Google Scholar
- Co-authors Med Uni Graz
- Peskar Bernhard
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- In 30 patients after kidney transplantation, 6-oxo-PGF1 alpha was examined in unextracted plasma by a specific radioimmunoassay. The material was divided into three groups. Patients with acute transplant rejection showing the highest 6-oxo-PGF1 alpha levels, patients with delayed transplant rejection having significantly lower plasma values and a third group of patients with stable transplant function. In these patients the plasma 6-oxo-PGF1 alpha-values were below the lower limit of detection (70 pg/ml). The enhanced 6-oxo-PGF1 alpha during rejection crisis could be interpreted as a self protection mechanism of vascular tissue which is, however, not sufficient in many cases, to prevent the irreversible rejection of the transplant.
- Find related publications in this database (using NLM MeSH Indexing)
- 6-Ketoprostaglandin F1 alpha - blood
- Acute Disease - blood
- Adult - blood
- Epoprostenol - metabolism
- Female - metabolism
- Graft Rejection - metabolism
- Humans - metabolism
- Kidney Transplantation - metabolism
- Male - metabolism
- Prostaglandins - metabolism