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Selected Publication:

Pfragner, R; Walser, V.
Long-term tissue culture of human pheochromocytomas.
EXP PATHOL-JENA. 1980; 18(7-8): 423-429. Doi: 10.1016/S0014-4908(80)80043-3
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Leading authors Med Uni Graz
Pfragner Roswitha
Co-authors Med Uni Graz
Siegl Veronika
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Abstract:
Two human pheochromocytomas were cultured for long periods. One was cultured for a year, the other is still growing after a cultivation time of seven months. Though decreasing with the age of cultures the cells contained catecholamines all the time. Catecholamines were demonstrated by electron microscope, by fluorescence histochemistry and by Vulpian's and Da Prada's methods. Both pheochromocytomas were responsive to Nerve Growth Factor and showed dose-dependent development of neurite-like processes.
Find related publications in this database (using NLM MeSH Indexing)
Adrenal Gland Neoplasms - pathology
Adult - pathology
Catecholamines - metabolism
Cell Separation - metabolism
Culture Techniques - metabolism
Cytoplasmic Granules - ultrastructure
Female - ultrastructure
Humans - ultrastructure
Male - ultrastructure
Nerve Growth Factors - pharmacology
Pheochromocytoma - pathology

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