Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Pfragner, R; Walser, V.
Long-term tissue culture of human pheochromocytomas.
EXP PATHOL-JENA. 1980; 18(7-8): 423-429.
Doi: 10.1016/S0014-4908(80)80043-3
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- Führende Autor*innen der Med Uni Graz
- Pfragner Roswitha
- Co-Autor*innen der Med Uni Graz
- Siegl Veronika
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- Abstract:
- Two human pheochromocytomas were cultured for long periods. One was cultured for a year, the other is still growing after a cultivation time of seven months. Though decreasing with the age of cultures the cells contained catecholamines all the time. Catecholamines were demonstrated by electron microscope, by fluorescence histochemistry and by Vulpian's and Da Prada's methods. Both pheochromocytomas were responsive to Nerve Growth Factor and showed dose-dependent development of neurite-like processes.
- Find related publications in this database (using NLM MeSH Indexing)
- Adrenal Gland Neoplasms - pathology
- Adult - pathology
- Catecholamines - metabolism
- Cell Separation - metabolism
- Culture Techniques - metabolism
- Cytoplasmic Granules - ultrastructure
- Female - ultrastructure
- Humans - ultrastructure
- Male - ultrastructure
- Nerve Growth Factors - pharmacology
- Pheochromocytoma - pathology