Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Than, NG; Romero, R; Hillermann, R; Cozzi, V; Nie, G; Huppertz, B.
Prediction of preeclampsia - a workshop report.
Placenta. 2008; 29 Suppl A(2):S83-S85
Doi: 10.1016/j.placenta.2007.10.008
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- Co-Autor*innen der Med Uni Graz
- Huppertz Berthold
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- Abstract:
- Understanding the mechanisms of disease responsible for the syndrome of preeclampsia as well as early risk assessment is still a major challenge. The concentrations of circulating proteins in maternal blood such as placental growth factor, soluble vascular endothelial growth factor receptor-1 and soluble endoglin are altered weeks before the onset of clinical symptoms of the syndrome. Recently, other proteins in maternal serum, such as activin A, inhibin A, PAPP-A, and PP13 have been suggested to be of value in first trimester risk assessment. Since preeclampsia is a syndrome, it seems unlikely that a single test will predict all forms of preeclampsia. This realization has led to the formulation of a new conceptual framework suggesting that a combination of markers (biochemical and/or biophysical) may be required to conduct comprehensive risk assessment for the syndrome.
- Find related publications in this database (using NLM MeSH Indexing)
- Biological Markers -
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- Pre-Eclampsia - diagnosis
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- Pregnancy -
- Risk Factors -