Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Gallina, A; Briganti, A; Chun, FK; Walz, J; Hutterer, GC; Erbersdobler, A; Eichelberg, C; Schlomm, T; Ahyai, SA; Perrotte, P; Saad, F; Montorsi, F; Huland, H; Graefen, M; Karakiewicz, PI.
Effect of autologous blood transfusion on the rate of biochemical recurrence after radical prostatectomy.
BJU Int. 2007; 100(6):1249-53
Doi: 10.1111/j.1464-410X.2007.07147.x
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- Co-Autor*innen der Med Uni Graz
- Ahyai Sascha
- Hutterer Georg
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- Abstract:
- OBJECTIVE: To test the association between autologous blood transfusion (ABT) and biochemical recurrence (BCR) after radical prostatectomy (RP) in a large group of contemporary patients. PATIENTS AND METHODS: We analysed 1291 patients treated with RP; Kaplan-Meier analysis was used to graphically explore the association between ABT and BCR. Cox regression models addressed the association between ABT and BCR in univariate and multivariate analyses, after adjusting for preoperative prostate specific antigen level, pathological Gleason sum, extracapsular extension, seminal vesicle invasion and lymph node invasion. RESULTS: Of all patients, 205 (15.4%) received perioperative ABT. The mean (median, range) follow-up was 43.2 (40.9, 0.3-145) months. BCR was recorded in 347 (26.9%) patients and the time to BCR was 25.2 (20.5, 0.3-107) months. Neither in univariate (P = 0.053) nor in multivariate (P = 0.2) Cox regression analyses was ABT a statistically significant or independent predictor of BCR. CONCLUSION: Perioperative ABT does not predispose to a higher rate of BCR in patients after RP.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult - administration & dosage
- Aged - administration & dosage
- Blood Loss, Surgical - administration & dosage
- Blood Transfusion, Autologous - adverse effects
- Epidemiologic Methods - administration & dosage
- Humans - administration & dosage
- Lymphatic Metastasis - administration & dosage
- Male - administration & dosage
- Middle Aged - administration & dosage
- Neoplasm Invasiveness - administration & dosage
- Neoplasm Recurrence, Local - blood, etiology, pathology
- Prognosis - administration & dosage
- Prostate-Specific Antigen - blood
- Prostatectomy - administration & dosage
- Prostatic Neoplasms - blood, pathology, surgery
- Treatment Outcome - administration & dosage
- Find related publications in this database (Keywords)
- autologous blood transfusion
- biochemical recurrence
- prostate cancer
- radical prostatectomy