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Selected Publication:
Urban, C; Becker, H; Mutz, I; Fritsch, G.
BCG-infection in chronic granulomatous disease (author's transl)
Klin Padiatr. 1980; 192(1):13-18
Doi: 10.1055/s-2008-1033853
(- Case Report)
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- Leading authors Med Uni Graz
- Urban Ernst-Christian
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- Abstract:
- A 7 year old boy developed in the newborn period a chronic suppurative process after routine BCG vaccination beginning at the site of the injection and spreading to the adjacent areas on neck and chin. A supraclavicular lymphadenopathy was also noted. Serial histological examinations revealed the typical histopathological pattern of tuberculosis and the boy received a tuberculostatic therapy for five years. During this time he suffered from multiple chronic bacterial infections which led to chronic granulomatous inflammations in different organs and to a fibrous pneumonitis with subsequent cor pulmonale. At the age of 6 years a negative NBT-test allowed the diagnosis of GCD. Consequently therapy with Sulfamethoxazol-Trimethoprim was started and the rate of infections diminished markedly.
- Find related publications in this database (using NLM MeSH Indexing)
- BCG Vaccine - adverse effects
- Biopsy - adverse effects
- Child - adverse effects
- Granulomatous Disease, Chronic - complications
- Humans - complications
- Lymph Node Excision - complications
- Lymphadenitis - complications
- Male - complications
- Pulmonary Fibrosis - complications
- Pulmonary Heart Disease - complications
- Tuberculosis, Lymph Node - complications