Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Neumann, RA; Knobler, RM; Aberer, E; Klein, W; Kocsis, F; Ott, E.
Abnormal epidermal changes after argon laser treatment.
J Am Acad Dermatol. 1991; 24(2 Pt 2):369-375
Doi: 10.1016/0190-9622(91)70055-7
(- Case Report)
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- Co-Autor*innen der Med Uni Graz
- Aberer Elisabeth
- Ott Erwin
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- Abstract:
- A 26-year-old woman with a congenital port-wine stain on the forehead was treated three times at 2-month intervals with an argon laser. Six months after the last treatment, moderate blanching and mild scaling confined to the treated area was observed. A biopsy specimen of the treated area revealed a significant decrease in ectatic vessels. However, epidermal changes similar to those of actinic keratosis with disorganized cell layers and marked cytologic abnormalities were seen. Analysis of peripheral blood lymphocytes for a defect in DNA repair was negative. Multiple, argon laser-induced photothermal effects may be responsible for the changes observed in our case and may lead to premalignant epidermal transformation.
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