Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
ABERER, W; ZIEGLER, V.
SOURCES OF ERROR IN THE INVITRO DIAGNOSTICS OF ALLERGIES - INFLUENCE OF TRANSPORT AND STORAGE OF BLOOD-SAMPLES ON THE DETECTION OF TOTAL-SPECIFIC AND ALLERGEN-SPECIFIC IGE
ALLERGOLOGIE. 1992; 15(10): 345-347.
Web of Science
- Führende Autor*innen der Med Uni Graz
- Aberer Werner
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- Abstract:
- Blood or serum samples from allergic patients were treated under conditions as they may occur during transportation to or storage in the laboratory. The influence of various temperatures, storage over prolonged time periods and cycles of freezing and thawing on the detectability of total- and allergen-specific IgE levels were evaluated. In parallel, radio- and enzyme-immunologic standard techniques (RIA, ELISA) were applied. No procedure, i.e. incubation for 2 days at 4, 20 or 37-degrees-C, repeated freezing cycles, prolonged storage or transport as full blood, with the exception of incubation at 56-degrees-C, exerted any negative influences on the IgE values. Bad test performance can thus hardly be explained by potential problems during transportation of the blood samples, since the IgE molecule seems to be less temperature-sensitive than is commonly assumed.
- Find related publications in this database (Keywords)
- IGE
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