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ABERER, W; ZIEGLER, V; ANEGG, B.
CONTACT ALLERGY TO KATHON - ELIMINATION OR DECLARATION
DERMATOSEN BERUF UMWELT. 1992; 40(3): 112-115.
Web of Science

Führende Autor*innen der Med Uni Graz: Aberer Werner
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Abstract:: No other chemical has probably released a flood of publications, both in the scientific literature and in the lay press in such a short time as the preservative Kathon CG. Patch test results in eczema patients have revealed sensitization rates ranging from 0. 6 7 up to 16.1 %; the problem of too high concentrations in toiletry products and even patch test substances, associated with a distinct degree of active sensitization, is well documented. And even the compromise of 100 ppm a.i. of Cl+Me-isothiazolinone for patch testing might cause clinically irrelevant results in a considerable number of patients. Numerous, reports have indicated the necessity of differential titrations and provocative use tests with both standardized and the patients own products in positive patch test patients. Despite this, many of the more than 50 publications in "Contact Dermatitis", dating from 1985 to 1990 and dedicated primarily to the Kathon-problem, based their conclusions on conventional patch test results alone. Kathon CG is definitely a potential antigen, but whether it is - upon correct application - a potent allergen remains yet to be elucidated.
Find related publications in this database (Keywords): CONTACT DERMATITIS; KATHON; ROAT