Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
FUCHS, T; ENDERS, F; PRZYBILLA, B; IPPEN, H; ABERER, W; BAUER, R; BOHM, I; SCHULZEDIRKS, A; FROSCH, PJ; PETERS, KP; GAILHOFER, G; STEFFAN, MA; WASSILEW, SW; HENSEL, O; GEHRING, W; LISCHKA, G; AGATHOS, M; BREIT, R; BAHMER, F; STARY, A; BRASCH, J.
CONTACT ALLERGY TO EUXYL-K-400 - RESULTS OF A MULTICENTER STUDY OF THE GERMAN-CONTACT-ALLERGY-GROUP (DKG)
DERMATOSEN BERUF UMWELT. 1991; 39(5): 151-153.
Web of Science
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- Co-Autor*innen der Med Uni Graz
- Aberer Werner
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- Abstract:
- 3726 patient (2294 females, 1432 males) in 15 clinics were patch tested with the preservative Euxyl(R) K 400 (1,2-dibrom-2,4-dicyanbutane and phenoxyethanol) from June 1989 to May 1990. The reactivity was low: Irritant (non-specific) reactions to dibromdicyanbutane (BCB) were seen in 12 (0.3%) cases, to Euxyl K 400 in six (0.16 %) and to phenoxyethanol in nine cases (0.24 %). Positive (allergic) reactions to Euxyl K 400 were determined in 36 (1.0 %), to dibromdicyanbutane in 30 (0.8 %), and to phenoxyethanol in one patient. In 17 cases (0.5 %), a current or past clinical relevance to these test results was established. Eight patients were masseurs/masseuses or of similar professions. The sensitization rate to Euxyl K 400 and especially to dibromdicyanbutane appears low at present. Euxyl K 400 is used increasingly instead of isothiazolinones in cosmetics. If the presently low risk of contact allergic reactions will change under these conditions is to be awaited.
- Find related publications in this database (Keywords)
- DIBROMDICYANBUTANE
- EUXYL-K-400
- PHENOXYETHANOL