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Gewählte Publikation:

Rzany, B; Przybilla, B; Jarisch, R; Aberer, W; Dietschi, R; Wüthrich, B; Bühler, B; Frosch, P; Rakoski, J; Kiehn, H.
Clinical characteristics of patients with repeated systemic reactions during specific immunotherapy with hymenoptera venoms. A retrospective study.
Allergy. 1991; 46(4):251-254 Doi: 10.1111/j.1398-9995.1991.tb00582.x
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Co-Autor*innen der Med Uni Graz
Aberer Werner
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Abstract:
In general, specific immunotherapy with hymenoptera venoms can be considered as safe, but occasionally there are patients who cannot reach the maintenance dose due to repeated systemic reactions (RSR) or who suffer from RSR during maintenance therapy. In a multicenter retrospective study comprising seven departments in Germany, Austria and Switzerland 23 patients with RSR were reported from approximately 3000 patients treated with hymenoptera venoms (bee and wasp venom to approximately equivalent frequency). From these, 22 were allergic to bee venom and only one to vespid venom. In general the clinical symptoms of RSR were milder than the initial reaction. But 4/23 (18%) exhibited cardiovascular reactions up to full shock. Neither anamnestic details, reactivity in skin tests or in vitro tests revealed a special pattern of patients with RSR. In some patients, however, an extremely high reactivity in the skin test was found and may indicate the possibility of further RSR.
Find related publications in this database (using NLM MeSH Indexing)
Adolescent -
Adult -
Anaphylaxis - etiology
Animals - etiology
Arthropod Venoms - adverse effects
Bee Venoms - adverse effects
Child - adverse effects
Female - adverse effects
Humans - adverse effects
Hymenoptera - adverse effects
Hypersensitivity - etiology
Immunotherapy - etiology
Male - etiology
Middle Aged - etiology
Retrospective Studies - etiology
Skin Tests - etiology
Wasp Venoms - adverse effects

Find related publications in this database (Keywords)
HYMENOPTERA VENOM ALLERGY
SPECIFIC IMMUNOTHERAPY
REPEATED SYSTEMIC REACTIONS
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