Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Wiche, G; Krepler, R; Artlieb, U; Pytela, R; Aberer, W.
Identification of plectin in different human cell types and immunolocalization at epithelial basal cell surface membranes.
Exp Cell Res. 1984; 155(1):43-49
Doi: 10.1016/0014-4827(84)90766-3
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- Co-Autor*innen der Med Uni Graz
- Aberer Werner
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- Abstract:
- The occurrence of plectin in various human tissues and cell lines was investigated using immunofluorescence microscopy and antibody gel overlay/immunoblotting techniques. Plectin was identified in all tissues and cell lines tested, namely placenta, kidney, cornea, foreskin and eyelid skin, skin fibroblasts, monocytes, keratinocytes and HeLa cells. In frozen sections of cornea and skin, plectin was found to be enriched at epithelial basal cell surface membranes. Consequently, antibodies to plectin could serve as a tool in the classification of mechanobullous diseases.
- Find related publications in this database (using NLM MeSH Indexing)
- Cell Line -
- Cornea - ultrastructure
- Desmosomes - metabolism
- Epithelium - ultrastructure
- Fluorescent Antibody Technique - ultrastructure
- Humans - ultrastructure
- Intermediate Filament Proteins - metabolism
- Molecular Weight - metabolism
- Plectin - metabolism
- Proteins - immunology
- Skin - ultrastructure