Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Aberer, W; Stingl, G; Wolff, K.
Stevens-Johnson syndrome and toxic epidermal necrolysis following intake of sulfonamides
Hautarzt. 1982; 33(9): 484-490.
(- Case Report)
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- Führende Autor*innen der Med Uni Graz
- Aberer Werner
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- Abstract:
- Sulfonamides, particularly in combination with trimethoprim, are among the most commonly prescribed antimicrobial chemotherapeutic agents since they are generally well tolerated and have a broad antibacterial spectrum. However, they are the most common cause of adverse cutaneous drug reactions, the most serious of which are the major variant of erythema multiforme, i.e. Stevens-Johnson-syndrome, and toxic epidermal necrolysis. In eight of 11 patients with Stevens-Johnson syndrome or toxic epidermal necrolysis seen in our department over a period of 4 years, sulfonamides were the most probable causative agent. The present report describes these eight patients and discusses the potential risks of sulfonamide therapy.
- Find related publications in this database (using NLM MeSH Indexing)
- Aged -
- Epidermal Necrolysis, Toxic - etiology
- Female - etiology
- Humans - etiology
- Male - etiology
- Middle Aged - etiology
- Stevens-Johnson Syndrome - chemically induced
- Sulfonamides - adverse effects