Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Rohrböck, RB; Hammer, J; Vogelsang, H; Talley, NJ; Hammer, HF.
Acupuncture has a placebo effect on rectal perception but not on distensibility and spatial summation: a study in health and IBS.
AMER J GASTROENTEROL. 2004; 99(10): 1990-1997.
Doi: 10.1111/j.1572-0241.2004.30028.x
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Hammer Heinz
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- Abstract:
- BACKGROUND: Recent data suggest that acupuncture has effects on gut physiology and perception. Spatial summation is a central mechanism of perception and describes the phenomenon that thresholds for perception are lower if more receptors are stimulated. OBJECTIVES: We assessed perception thresholds for rectal distension and cutaneous referral of symptoms, while inflating one or two rectal balloons and the effect of both electro-acupuncture and placebo-acupuncture on rectal distensibility, perception, and spatial summation. METHODS: A tube with two barostat balloons was placed in the rectum of 12 healthy subjects and nine irritable bowel syndrome (IBS) patients with rectal symptoms. Volume-controlled stepwise distension of the distal balloon only or both balloons was performed first as a control, and thereafter with simultaneous placebo- or electro-acupuncture in dermatomes S3 and S4. A symptom questionnaire and anatomic questionnaire was completed during each distension. RESULTS: Rectal elastance increased from 42.0 +/- 19.6 log mmHg/ml during one-balloon distension to 59.6 +/- 33.1 log mmHg/ml during two-balloon distension (p < 0.05) in healthy subjects, and from 48.8 +/- 14.4 log mmHg/ml (one balloon) to 77.6 +/- 24.2 log mmHg/ml (p < 0.001) in patients with IBS. Electro-acupuncture had no effect on rectal sensation, elastance, and cutaneous referral when compared to placebo-acupuncture. However, acupuncture (both electro- and placebo-) increased volume thresholds for sensation compared to control experiments, while objective parameters like rectal tone and elastance were unaltered. CONCLUSION: Acupuncture has a placebo effect on rectal perception but has no effect on rectal distensibility and visceral referral. Spatial summation affected both rectum distensibility and perception, but was also not altered by acupuncture.
- Find related publications in this database (using NLM MeSH Indexing)
- Acupuncture Therapy -
- Adult -
- Female -
- Humans -
- Inflammatory Bowel Diseases - therapy
- Male - therapy
- Placebo Effect - therapy
- Rectum - physiology
- Sensory Thresholds - physiology
- Space Perception - physiology