Medizinische Universität Graz - Research portal
Selected Publication:
Böhm, M; Diet, F; Pieske, B; Erdmann, E.
h-ANF does not play a role in the regulation of myocardial force of contraction.
Life Sci. 1988; 43(16):1261-1267
Doi: 10.1016/0024-3205(88)90580-2
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- Co-authors Med Uni Graz
- Pieske Burkert Mathias
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- Abstract:
- In the present study, h-ANF failed to reduce myocardial force of contraction alone and in the presence of isoprenaline. This lack of effect was observed in electrically driven, isolated human papillary muscle strips and rat papillary muscles. In contrast, adenosine and carbachol exerted antiadrenergic actions in rat and human myocardium. It is concluded that h-ANF obviously does not play a role in the regulation of human and rat myocardial force of contraction, whereas adenosine and carbachol are capable to produce antiadrenergic effects in the human and rat myocardium.
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