Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Koestenberger, M; Nagel, B; Gamillscheg, A; Temmel, W; Cvirn, G; Beitzke, A.
Myocardial infarction in an adolescent: anomalous origin of the left main coronary artery from the right coronary sinus in association with combined prothrombotic defects.
PEDIATRICS. 2007; 120(2): e424-e427.
Doi: 10.1542/peds.2006-3181
(- Case Report)
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Koestenberger Martin
- Co-Autor*innen der Med Uni Graz
- Beitzke Albrecht
- Cvirn Gerhard
- Gamillscheg Andreas
- Nagel Bert Hermann Philipp
- Temmel Werner
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- We present the case of a 15-year-old boy with clinical features of an acute myocardial infarction. Angiography revealed a complete obstruction of the left main coronary artery. A coronary-aorto-bypass graft was undertaken immediately. Cardiac computed tomography demonstrated an anomalous origin of the left main coronary artery from the right coronary sinus of the aorta. A thrombophilic state with a heterozygote genotype for prothrombin G20210 mutation, a C677T methylenetetrahydrofolate reductase gene mutation, and a protein C type 1 deficiency was detected. No other embolic source could be identified. The patient recovered with persistent left ventricular dysfunction. He is now taking the anticoagulant warfarin. Combined prothrombotic defects in combination with additional risk factors such as coronary anomalies can lead to myocardial infarction even in children and adolescents.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Coronary Angiography - methods
- Coronary Vessel Anomalies - complications
- Humans - complications
- Male - complications
- Mutation - complications
- Myocardial Infarction - etiology
- Prothrombin - genetics
- Thrombophilia - complications
- Ventricular Dysfunction, Left - etiology
- Find related publications in this database (Keywords)
- myocardial infarction
- adolescent
- coronary anomaly
- prothrombotic defects