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Hofmann, H; Schmut, O.
The different effects of fe(II)- and fe(III)-ions on the hyaluronic acid of the vitreous body (author's transl)
Klin Monatsbl Augenheilkd. 1978; 172(2): 261-263.
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Co-authors Med Uni Graz
Schmut Otto
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Abstract:
Fe(II)-ions reduce the viscosity of a hyaluronic acid solution but do not form a precipitate. Fe(III)-ions only slightly lower the viscosity of hyaluronic acid solutions but cause a brown, water-insoluble iron-hyaluronic acid precipitate. After adding ascorbic acid--concentrate the pH-value as in vitreous body--to the reaction solution, Fe(III)-ions reduce the viscosity too. The iron-hyalurnic acid complex is also destroyed by ascorbate. Therefore, the ascorbate of the vitreous humor plays an important role in the generation of siderosis bulbi.
Find related publications in this database (using NLM MeSH Indexing)
Animals -
Ascorbic Acid - metabolism
Cattle - metabolism
Hyaluronic Acid - metabolism
Hydrogen-Ion Concentration - metabolism
Iron - pharmacology
Viscosity - pharmacology
Vitreous Body - drug effects

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