Selected Publication:
Hofmann, H; Schmut, O.
The different effects of fe(II)- and fe(III)-ions on the hyaluronic acid of the vitreous body (author's transl)
Klin Monatsbl Augenheilkd. 1978; 172(2): 261-263.
Web of Science
PubMed
- Co-authors Med Uni Graz
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Schmut Otto
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- Abstract:
- Fe(II)-ions reduce the viscosity of a hyaluronic acid solution but do not form a precipitate. Fe(III)-ions only slightly lower the viscosity of hyaluronic acid solutions but cause a brown, water-insoluble iron-hyaluronic acid precipitate. After adding ascorbic acid--concentrate the pH-value as in vitreous body--to the reaction solution, Fe(III)-ions reduce the viscosity too. The iron-hyalurnic acid complex is also destroyed by ascorbate. Therefore, the ascorbate of the vitreous humor plays an important role in the generation of siderosis bulbi.
- Find related publications in this database (using NLM MeSH Indexing)
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Animals -
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Ascorbic Acid - metabolism
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Cattle - metabolism
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Hyaluronic Acid - metabolism
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Hydrogen-Ion Concentration - metabolism
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Iron - pharmacology
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Viscosity - pharmacology
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Vitreous Body - drug effects