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Selected Publication:

Hofmann, H; Schmut, O; Sterk, H; Kopp, H.
Spin-lattice-relaxationtime-T1 measurements of hyaluronic acid (author's transl)
Z Naturforsch [C]. 1979; 34(7-8): 508-511.
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Co-authors Med Uni Graz
Schmut Otto
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Abstract:
Reductions with [3H5NaBH4 proof that the decrease in viscosity of hyaluronic acid solutions caused by lowering the pH does not depend on a depolymerisation of hyaluronic acid. At the same time investigations at different pH-values, show a sigmoide increase of the Spin-Lattice-Relaxationtime T1. This increase depends on a progressive aggregation of the hyaluronic acid molecule. The effect seems to be induced by the decrease of ionization of the carboxylgroups, by acidification of the solution.
Find related publications in this database (using NLM MeSH Indexing)
Carbohydrate Conformation -
Electron Spin Resonance Spectroscopy -
Hyaluronic Acid -
Hydrogen-Ion Concentration -
Thermodynamics -
Viscosity -

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