Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Stauber, RE; Lackner, C.
Noninvasive diagnosis of hepatic fibrosis in chronic hepatitis C.
World J Gastroenterol. 2007; 13(32): 4287-4294.
Doi: 10.3748/wjg.v13.i32.4287
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- Führende Autor*innen der Med Uni Graz
- Stauber Rudolf
- Co-Autor*innen der Med Uni Graz
- Lackner Karoline
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- Abstract:
- Assessment of hepatic fibrosis is important for determining prognosis, guiding management decisions, and monitoring disease. Histological evaluation of liver biopsy specimens is currently considered the reference test for staging hepatic fibrosis. Since liver biopsy carries a small but significant risk, noninvasive tests to assess hepatic fibrosis are desirable. This editorial gives an overview on noninvasive methods currently available to determine hepatic fibrosis and their diagnostic accuracy for predicting significant fibrosis and cirrhosis in chronic hepatitis C. Based on available data, the performance of simple tests derived from routine laboratory parameters appears to be similar to that of more complex and expensive fibrosis panels. Transient elastography seems more accurate than blood tests for diagnosing cirrhosis.
- Find related publications in this database (using NLM MeSH Indexing)
- Biological Markers - metabolism
- Biopsy - metabolism
- Elasticity - metabolism
- Hepatitis C, Chronic - complications
- Humans - complications
- Liver - enzymology
- Liver Cirrhosis - diagnosis
- Predictive Value of Tests - diagnosis
- Find related publications in this database (Keywords)
- noninvasive fibrosis tests
- significant fibrosis
- cirrhosis
- biomarkers
- transient elastography