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SHR Neuro Krebs Kardio Lipid Stoffw Microb

Döser, S; März, W; Reinecke, MF; Ringleb, P; Schultz, A; Schwandt, P; Becker, HJ; Bönner, G; Buerke, M; Diener, HC; Gohlke, H; Keil, U; Ringelstein, EB; Steinmetz, A; Gladisch, R; Wehling, M.
Recommendations for statin therapy in the elderly
Internist (Berl). 2004; 45(9):1053-1062 Doi: 10.1007/s00108-004-1268-6
Web of Science PubMed FullText FullText_MUG

Co-Autor*innen der Med Uni Graz: März Winfried
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Abstract:: Elderly patients are significantly less likely to receive statins than younger patients possibly because of doubts regarding compliance or concerns regarding the increased likelihood of adverse events and drug interactions. Poor compliance can be expected especially in patients suffering from dementia or depression as well as those whose stage of cardiovascular disease exhibits few symptoms. On the other hand, the clinical significance of CHD events is high in the elderly, and 80% of coronary deaths occur in patients aged over 65 years. The average statistical life expectancy of elderly and old patients is often underestimated. The HPS and PROSPER studies showed that statins reduce mortality and morbidity even in very elderly individuals with a high global cardiovascular risk and/or CAD. Patients up to the age of 79 years should be treated according to the same guidelines as younger patients. Statin therapy should only be considered for patients aged 80 years and older who are at a very high risk for cardiovascular events.
Find related publications in this database (using NLM MeSH Indexing): Aged -; Aged, 80 and over -; Anticholesteremic Agents - adverse effects; Coronary Disease - drug therapy; Drug Utilization - trends; Female - trends; Forecasting - trends; Germany - trends; Humans - trends; Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects; Hypercholesterolemia - drug therapy; Life Expectancy - drug therapy; Male - drug therapy; Middle Aged - drug therapy; Patient Compliance - drug therapy; Treatment Outcome - drug therapy
Find related publications in this database (Keywords): hypercholesterolemia; statins; elderly patient; efficacy