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Selected Publication:

Rinner, I; Schauenstein, K.
Detection of choline-acetyltransferase activity in lymphocytes.
J Neurosci Res. 1993; 35(2):188-191 Doi: 10.1002/jnr.490350209
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Co-authors Med Uni Graz
Schauenstein Konrad
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Abstract:
The cholinergic system takes part in the immune-neuroendocrine integration. Lymphocytes have been found to express muscarinic and nicotinic cholinergic receptors, as well as acetylcholine-esterase on their surface, and cholinergic agents modulate immune functions in vitro and in vivo. In the present study we provide evidence that purified organ resident and circulating lymphocytes, as well as various lymphoid cell lines derived from different species, exhibit choline-acetyltransferase activity and, therefore, have the potential to produce the neurotransmitter acetylcholine.
Find related publications in this database (using NLM MeSH Indexing)
Animals -
Cell Line -
Choline O-Acetyltransferase - analysis
Humans - analysis
Lymphocytes - enzymology
Male - enzymology
Mice - enzymology
Rats - enzymology
Rats, Sprague-Dawley - anatomy and histology
Spleen - cytology
Thymus Gland - cytology
Tumor Cells, Cultured - cytology

Find related publications in this database (Keywords)
Immune-Neuroendocrine Integration
Muscarinic Receptors
Nicotinic Receptors
Acetylcholine-Esterase
Cholinergic Receptors
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