Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Schober, T; Wenzel, K; Feichtinger, M; Schwingenschuh, P; Strebel, A; Krausz, G; Pfurtscheller, G.
Restless legs syndrome: changes of induced electroencephalographic beta oscillations-an ERD/ERS study.
SLEEP. 2004; 27(1): 147-150.
Doi: 10.1093/sleep/27.1.147
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- Co-Autor*innen der Med Uni Graz
- Feichtinger Michael
- Schwingenschuh Petra
- Wenzel Karoline
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- Abstract:
- Study Objectives: Primary or idiopathic restless legs syndrome (RLS) is a sensorimotor disorder of unknown neurophysiologic origin. Setting and Patients: Ten patients with RLS and 10 healthy control subjects were investigated. Postmovement beta oscillations (event-related synchronization, ERS) induced by movement of the right index finger were measured by electroencephalography and analyzed. Results: We found differences between patients and controls for ERS values at electrode positions C3 and Cz. At C3, the lower beta band ERS (14-20 Hz) in the RLS group was 101.2% compared with 27.5% in the control group (P < .05); in the upper beta band, (20-32 Hz) the findings were 97.8% and 29.0%, respectively, for the RLS and control groups (P < .01). At electrode Cz, no significant difference could be found in the lower beta band, but, for the upper beta band, patients showed signifi- cantly higher values than did the healthy control subjects (68.5% vs 25.6%, P < .05). Conclusions: We interpret these findings as a higher need for motor-cortical inhibition in RLS patients due to an increased level of excitation by motor-cortex activation and input from neighboring functionally interrelated cortical areas (hand and foot region). These results reveal new potentially important findings of the neurophysiologic and pathophysiologic origin of primary RLS.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Cortical Synchronization -
- Electroencephalography -
- Evoked Potentials - physiology
- Female - physiology
- Fingers - physiology
- Humans - physiology
- Male - physiology
- Middle Aged - physiology
- Movement - physiology
- Restless Legs Syndrome - diagnosis
- Find related publications in this database (Keywords)
- restless legs syndrome
- ERD
- ERS
- electroencephalography
- neurophysiologic/pathophysiologic origin
- pathogenesis