Medizinische Universität Graz - Research portal
Selected Publication:
Schmut, O; Gruber, E; el-Shabrawi, Y; Faulborn, J.
Destruction of human tear proteins by ozone.
Free Radic Biol Med. 1994; 17(2):165-169
Doi: 10.1016/0891-5849(94)90112-0
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PubMed
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- Leading authors Med Uni Graz
- Schmut Otto
- Co-authors Med Uni Graz
- El-Shabrawi Yosuf
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- Abstract:
- By an in vitro system human tears from healthy donors were exposed in a sealed vessel to a single dose of ozone. A marked destruction of tear proteins by ozone was observed as indicated by the disappearance of the protein pattern in polyacrylamide gel electrophoresis compared with the control. Lysozyme, a significant protein in tears, was demonstrated to be susceptible to degradation by O3. The destruction of tear proteins by ozone can be determined quantitatively by radial immunodiffusion as shown for human tear albumin. Variations of ozone concentrations and reaction time showed that destruction of tear proteins by ozone depended on the ozone concentration and occurred within a few minutes of exposure of tears to ozone.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Albumins - drug effects
- Female - drug effects
- Humans - drug effects
- Immunoglobulins - drug effects
- Male - drug effects
- Muramidase - drug effects
- Ozone - toxicity
- Proteins - drug effects
- Reference Values - drug effects
- Tears - chemistry
- Find related publications in this database (Keywords)
- Ozone
- Human Tear Fluid
- Destruction
- Dry Eye Syndrome
- Free Radicals