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SHR Neuro Cancer Cardio Lipid Metab Microb

Archelos, JJ.
Treatment options in painful diabetic polyneuropathy
Wien Klin Wochenschr. 2007; 119(7-8):205-216 Doi: 10.1007/s00508-007-0795-2
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Leading authors Med Uni Graz
Archelos-Garcia Juan-Jose
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Abstract:
Distal symmetrical polyneuropathy is the most frequent manifestation of diabetic neuropathy and crucially contributes to the development of diabetic foot and subsequent amputation in 70 to 80% of all cases. In 10 to 15% of affected patients considerable pain is present, in particular in early diabetic polyneuropathy. This review summarizes evidence based data on prevention, neuroregenerative, and symptomatic treatment of painful diabetic polyneuropathy. The most important clinical trials on treatment and prevention are presented. Conclusions from these clinical studies in particular detailed treatment recommendations including dosage and side effects are given. Combined treatments and escalating therapies for severe pain syndromes are discussed.
Find related publications in this database (using NLM MeSH Indexing)
Analgesics - therapeutic use
Anticonvulsants - therapeutic use
Diabetic Neuropathies - complications
Humans - complications
Hyperalgesia - drug therapy
Physician's Practice Patterns - drug therapy
Practice Guidelines as Topic - drug therapy
Serotonin Agonists - therapeutic use

Find related publications in this database (Keywords)
diabetic polyneuropathy
neuropathic pain
treatment
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