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Kahn, J; Müller, H; Marte, W; Rehak, P; Wasler, A; Prenner, G; Tscheliessnigg, K.
Establishing extracorporeal membrane oxygenation in a university clinic: case series.
J Cardiothorac Vasc Anesth. 2007; 21(3): 384-387. Doi: 10.1053/j.jvca.2006.12.022
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Führende Autor*innen der Med Uni Graz
Kahn Judith
Co-Autor*innen der Med Uni Graz
Marte Wolfgang
Müller Helmut
Prenner Günther
Rehak Peter
Tscheliessnigg Karlheinz
Wasler Andrae
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Abstract:
OBJECTIVES: Although extracorporeal membrane oxygenation (ECMO) is well established for respiratory failure in neonates, application in adults is still considered controversial. The survival of patients with acute respiratory distress syndrome and ECMO therapy is 50% to 70%. DESIGN: A retrospective analysis of 10 patients, who were placed on ECMO from September 2004 to December 2005, was performed. SETTING: University clinic. INTERVENTIONS: Venoarterial ECMO was established in 7 patients, venovenous ECMO in 2 patients, and combined venoarterial and venovenous ECMO in 1 patient. MEASUREMENTS AND MAIN RESULTS: Indications were pneumonia, acute respiratory distress syndrome, near drowning, pericardial tamponade with shock lung, right-heart failure after heart transplantation, shock lung after cardiopulmonary resuscitation, and right-heart failure in chronic thromboembolic pulmonary hypertension. Median maintenance of ECMO therapy was 56.5 hours (range, 36-240). The median Murray score was 3.3 for survivors and 4 for nonsurvivors. Overall mortality was 30%; 70% were weaned from ECMO and survived until discharge. Median pre-ECMO risk for fatal outcome according to Hemmila was 0.43 for survivors and 0.92 for nonsurvivors (p < 0.02). In 2 cases, surgical reintervention was necessary because of bleeding in one, and a side switch of the cannulae had to be performed because of femoral venous thrombosis in the other. CONCLUSIONS: ECMO has been shown to be a successful therapy for acute respiratory distress syndrome when conventional strategies have failed. Pre-ECMO risk assessment may be useful in the evaluation of patients.
Find related publications in this database (using NLM MeSH Indexing)
Adult -
Extracorporeal Membrane Oxygenation - adverse effects
Female - adverse effects
Humans - adverse effects
Male - adverse effects
Middle Aged - adverse effects
Retrospective Studies - adverse effects
Risk Assessment - adverse effects

Find related publications in this database (Keywords)
extracorporeal membrane oxygenation
acute respiratory failure
acute respiratory distress syndrome
ECMO
ARDS
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