Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Kushner, MJ; Chawluk, J; Fazekas, F; Mandell, B; Burke, A; Jaggi, J; Rosen, M; Reivich, M.
Cerebral blood flow in systemic lupus erythematosus with or without cerebral complications.
Neurology. 1987; 37(10):1596-1598
Doi: 10.1212/WNL.37.10.1596
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- Co-Autor*innen der Med Uni Graz
- Fazekas Franz
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- Abstract:
- We measured mean cerebral blood flow (CBF) in 25 lupus patients using the xenon-133 method. The CBF was normal in lupus patients without cerebral disease and also in CNS lupus patients in remission. The CBF was lower than normal during bouts of cerebral lupus (p less than 0.001). Repeat studies showed a stereotyped pattern consisting of depressed CBF during exacerbation of CNS disease and normalization of CBF during remission (p less than 0.01). These results show that CBF is a sensitive indicator of activity of CNS disease and that the direction of change in CBF reflects the clinical course of CNS lupus.
- Find related publications in this database (using NLM MeSH Indexing)
- Brain Diseases - complications
- Cerebrovascular Circulation - drug effects
- Female - drug effects
- Humans - drug effects
- Lupus Erythematosus, Systemic - complications
- Male - complications
- Prednisone - therapeutic use