Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Pirker, R; Goldstein, LJ; Ludwig, H; Linkesch, W; Lechner, C; Gottesman, MM; Pastan, I.
Expression of a multidrug resistance gene in blast crisis of chronic myelogenous leukemia.
Cancer Commun. 1989; 1(2):141-144
Doi: 10.3727/095535489820875354
(- Case Report)
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- Co-Autor*innen der Med Uni Graz
- Linkesch Werner
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- Abstract:
- Three of four patients with chronic myelogenous leukemia in blast crisis were found to express the multidrug resistance (MDR1) gene in their blast cells. Expression of the MDR1 gene may contribute to the poor response of these patients to chemotherapy.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
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- Blast Crisis - genetics
- Bone Marrow - pathology
- Drug Resistance - genetics
- Female - genetics
- Gene Expression - genetics
- Humans - genetics
- Leukemia, Myeloid, Chronic - drug therapy
- Male - drug therapy
- Middle Aged - drug therapy
- RNA, Neoplasm - genetics