Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Kübböck, J; Ludwig, H; Aiginger, P; Linkesch, W; Pötzi, P.
Treatment of metastasizing breast cancer with aminoglutethimide
ACTA MED AUST. 1982; 9(5-6): 221-226.
Web of Science
PubMed
- Co-Autor*innen der Med Uni Graz
- Linkesch Werner
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- Abstract:
- Aminoglutethimide was applied for treatment of 10 patients (8 postmenopausal, 2 ovariectomized) with metastasizing breast cancer. The patients were extensively pretreated with cytostatic and hormonal measurements and already completely resistant to these therapies. Using aminoglutethimide (500-1000 mg daily) plus additional substitution with 20-40 mg hydrocortisone one complete and three partial remissions could be achieved. Stabilization was observed in 3 cases. The duration of remission varied between 4-8 months in 3 cases and lasted one month in a further patient.
- Find related publications in this database (using NLM MeSH Indexing)
- Aged -
- Aminoglutethimide - adverse effects
- Ataxia - chemically induced
- Breast Neoplasms - drug therapy
- Carcinoembryonic Antigen - analysis
- Drug Resistance - analysis
- Estradiol - blood
- Exanthema - chemically induced
- Female - chemically induced
- Humans - chemically induced
- Hydrocortisone - therapeutic use
- Middle Aged - therapeutic use
- Neoplasm Metastasis - therapeutic use