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SHR Neuro Cancer Cardio Lipid Metab Microb

Stenger, MB; Evans, JM; Patwardhan, AR; Moore, FB; Hinghofer-Szalkay, H; Rossler, A; Ziegler, MG; Knapp, CF.
Artificial gravity training improves orthostatic tolerance in ambulatory men and women
ACTA ASTRONAUT. 2007; 60(4-7): 267-272. Doi: 10.1016/j.actaastro.2006.08.008
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Co-authors Med Uni Graz: Hinghofer-Szalkay Helmut; Rössler Andreas
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Abstract:: Orthostatic intolerance (01) continues to be a problem experienced by astronauts upon return from spaceflight. Artificial gravity (AG) training via short radius centrifugation has been suggested as a countermeasure to this OI. The purpose of our research was to determine effects of three weeks of intermittent (+1 to +2.5 G(Z) for 35 min/day) AG exposure on normal, ambulatory men and women. The results of this study indicate that 3 weeks of AG training improved orthostatic tolerance in a group of 14 men and 12 women by an average of 13.6%. This improvement was associated with a decrease in arterial pressure and vascular resistance, and increases in stroke volume and low frequency (0.04-0.15 Hz) arterial pressure and heart rate spectral power. These results suggest that improvement may be attributable to increased venous return possibly as a function of increased stress-induced sympathetic activity and/or vascular sympathetic responsiveness. (c) 2006 Elsevier Ltd. All rights reserved.
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