Schmid, P; Pilger, E; Goebel, R; Pessenhofer, H; Schwaberger, G.
Ergospirometric studies on patients with diabetes mellitus and the effect of biguanides on physical performance
Acta Med Austriaca. 1978; 5(3): 93-95.
PubMed
24 diabetic patients had submaximal exercise testing before, and 4 days after, biguanide treatment. Biguanide treatment resulted in a significantly decreased exercise capacity. This is explained by increased anaerobic energy production, which results in a decrease of the performance of an individual.
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