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SHR Neuro Cancer Cardio Lipid Metab Microb

Buritica, C; Serrano, M; Zuluaga, A; Arrabal, M; Regauer, S; Nogales, FF.
Mixed epithelial and stromal tumour of the kidney with luteinised ovarian stroma.
J Clin Pathol. 2007; 60(1):98-100 Doi: 10.1136/jcp.2005.031294 (- Case Report) [OPEN ACCESS]
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Co-authors Med Uni Graz: Regauer Sigrid
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Abstract:: We report a case of a 9-cm mixed epithelial and stromal tumour of the kidney in an obese 70-year-old woman with diabetes. The ovarian-type stroma had a spindle cell component that was positive for progesterone receptors and had the hitherto unreported presence of abundant foci of luteinised stromal cells with characteristic immunohistochemical positivity to alpha-inhibin, calretinin, aromatase and gonadotropin-releasing hormone (GnRH) receptors. We conclude that the stromal component is identical to ovarian cortical stroma. We believe that ovarian-type stroma occurs in extragenital tumours as a result of an epithelial-stromal interaction in an environment of hormonal hyperstimulation.
Find related publications in this database (using NLM MeSH Indexing): Aged -; Diabetes Mellitus, Type 2 - complications; Female - complications; Humans - complications; Kidney Neoplasms - etiology; Mixed Tumor, Malignant - etiology; Neoplasms, Glandular and Epithelial - etiology; Obesity - complications; Stromal Cells - pathology