Gewählte Publikation:
März, W; Trommlitz, M; Gross, W.
Differential turbidimetric assay for subpopulations of lipoproteins containing apolipoprotein A-I.
J Clin Chem Clin Biochem. 1988; 26(9):573-578
Doi: 10.1515/cclm.1988.26.9.573
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- Führende Autor*innen der Med Uni Graz
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März Winfried
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- Abstract:
- A differential immunoturbidimetric procedure for the quantitation of apolipoprotein A-I associated with lipoproteins LpA (containing both apolipoprotein A-I and apolipoprotein A-II) and with lipoproteins LpA-I (containing apolipoprotein A-I but no apolipoprotein A-II) is presented. Lipoproteins containing apolipoprotein A-II are precipitated with an anti-apolipoprotein A-II antibody. The resulting immunoprecipitate is sedimented and LpA-IA-I is measured in the supernate. Whereas LpA-IA-I concentrations differed significantly between normolipidaemic men and women (0.75 and 1.00 g/l, respectively), there was virtually no sex related difference in LpAA-I (0.83 and 0.88 g/l, respectively). LpA-IA-I was predominantly correlated with HDL2-cholesterol (rs = 0.630), whereas LpAA-I was statistically associated with HDL3 (rs = 0.417).
- Find related publications in this database (using NLM MeSH Indexing)
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Apolipoprotein A-I -
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Apolipoprotein A-II -
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Apolipoproteins A - blood
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Humans - blood
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Immunoelectrophoresis, Two-Dimensional - blood
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Lipoproteins - blood
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Lipoproteins, HDL - blood
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Lipoproteins, HDL3 - blood
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Nephelometry and Turbidimetry - blood