Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Löw-Friedrich, I; Grützmacher, P; März, W; Bergmann, M; Schoeppe, W.
Long-term echocardiographic examinations in chronic hemodialysis patients substituted with recombinant human erythropoietin.
Blood Purif. 1990; 8(5):272-278
Doi: 10.1159/000169978
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- Co-Autor*innen der Med Uni Graz
- März Winfried
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- Abstract:
- Cardiomegaly and impaired cardiac function induced by renal anemia are frequent findings in patients with chronic renal failure. The present investigation was performed to study the cardiac effects of a therapy with recombinant human erythropoietin in patients on maintenance hemodialysis. Echocardiographic examinations showed a decrease in cardiac size and left-ventricular mass continuously over 12 months of effective erythropoietin substitution. Cardiac output was reduced, and ejection fraction and myocardial contractility increased. The development of aggravation of arterial hypertension did not counteract the beneficial effects of erythropoietin on cardiac performance.
- Find related publications in this database (using NLM MeSH Indexing)
- Cardiomegaly - drug therapy
- Echocardiography - drug effects
- Erythropoietin - adverse effects
- Female - adverse effects
- Heart - drug effects
- Humans - drug effects
- Hypertension - chemically induced
- Male - chemically induced
- Recombinant Proteins - therapeutic use
- Renal Dialysis - adverse effects
- Time Factors - adverse effects
- Find related publications in this database (Keywords)
- RECOMBINANT HUMAN ERYTHROPOIETIN
- ECHOCARDIOGRAPHY
- CHRONIC HEMODIALYSIS
- CARDIAC SIZE
- LEFT-VENTRICULAR MASS
- MYOCARDIAL CONTRACTILITY