März, W; Cezanne, S; Gross, W.
Phenotyping of apolipoprotein E: immunoblotting after isoelectric focusing in immobilized pH gradients
Klin Wochenschr. 1990; 68 Suppl 22(5): 113-114.
Web of SciencePubMed
Apolipoprotein E is a major ligand for cellular lipoprotein receptors and plays an important role in the catabolism of triglyceride-rich lipoproteins. The polymorphism of apo E is associated with familial dysbetalipoproteinemia, LDL-cholesterol, and cardiovascular risk. In this report a method for the analysis of apo E isoforms in immobilized pH gradients is presented that does not require isolation apo E containing lipoproteins by ultracentrifugation.
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